KREATYNA a HMB - cytat

Miętki, ja nie za bardzo mam czas na szperanie... Napisz do Lonzy - oni Ci prześlą całą petardę badań!

na stronie mti sa wszystkie tego typu komercyjne badania..

jako ze ostatnio szukam dosc sporo w badaniach

moze toto ??

chco nie potwierdza to wplywu antykatabolicznego u osob ternujacych wskazuje na takowe zastosowanie u soosb nietrenujacych przed eksperymentm

Beta-hydroxy-beta-methylbutyrate (HMB) supplementation and the promotion of muscle growth and strength.

Slater GJ, Jenkins D.

Department of Physiology, Sports Science Sports Medicine Centre, Australian Institute of Sport, Canberra, Australian Capital Territory. [email protected]

Beta-hydroxy beta-methylbutyrate (HMB), a metabolite of the essential amino acid leucine, is one of the latest dietary supplements promoted to enhance gains in strength and lean body mass associated with resistance training. Unlike anabolic hormones that induce muscle hypertrophy by increasing muscle protein synthesis, HMB is claimed to influence strength and lean body mass by acting as an anticatabolic agent, minimising protein breakdown and damage to cells that may occur with intense exercise. Research on HMB has recently tested this hypothesis, under the assumption that it may be the active compound associated with the anticatabolic effects of leucine and its metabolites. While much of the available literature is preliminary in nature and not without methodological concern, there is support for the claims made regarding HMB supplementation, at least in young, previously untrained individuals. A mechanism by which this may occur is unknown, but research undertaken to date suggests there may be a reduction in skeletal muscle damage, although this has not been assessed directly. The response of resistance trained and older individuals to HMB administration is less clear. While the results of research conducted to date appear encouraging, caution must be taken when interpreting outcomes as most manuscripts are presented in abstract form only, not having to withstand the rigors of peer review. Of the literature reviewed relating to HMB administration during resistance training, only 2 papers are full manuscripts appearing in peer reviewed journals. The remaining 8 papers are published as abstracts only, making it difficult to critically review the research. There is clearly a need for more tightly controlled, longer duration studies to verify if HMB enhances strength and muscular hypertrophy development associated with resistance training across a range of groups, including resistance trained individuals.

innymi słowy lepiej co jakiś czas ...(przerwa chyba na 5-6 tyg - zresztą można i dłuższą przerwę zrobić)... powtórzyć cykl kreatyną niż ładowac $ w droższy HMB ? ?

a tutaj bardziej ogolnie o suplach i ich dzialaniu

Nutritional supplements to increase muscle mass.

Clarkson PM, Rawson ES.

Department Exercise Science, University of Massachusetts, Amherst 01003, USA.

Although nutritional supplements purported to increase muscle mass are widely available at health food stores, gyms, by mail order, and over the Internet, many of these supplements have little or no data to support their claims. This article reviews the theory and research behind popular nutritional supplements commonly marketed as muscle mass builders. Included are the minerals chromium, vanadyl sulfate, and boron, the steroid hormone dehydroepiandrosterone (DHEA), beta-methyl-hydroxy-beta-methylbutyrate (HMB), creatine, protein supplements, and amino acids. Research has shown that chromium vanadyl sulfate, and boron do not appear to be effective in increasing lean body mass. The few studies examining DHEA have not supported the claim of increased muscle gain. Preliminary work on HMB supports an anticatabolic effect, but only one human study is currently available. Many studies reported increased body mass and several have reported increased lean body mass following creatine ingestion. This weight gain is most likely water retention in muscle but could also be due to some new muscle protein. Although athletes have a greater protein requirement than sedentary individuals, this is easily obtained through the diet, negating the use of protein supplements. Studies on amino acids have not supported their claim to increase growth hormone or insulin secretion. Nutritional supplements can be marketed without FDA approval of safety or effectiveness. Athletes who choose to ingest these supplements should be concerned with unsubstantiated claims, questionable quality control, and safety of long-term use

Sławku ale w skład błon biologicznych wchodzą także fosfolipidy i bez nich HMB tez nie zapewni calkowitej obrony przed wypuszczeniem enzymow lizosomalnych ?


Jakie jest jeszcze działanie antykataboliczne hmb ?

Sławku mam teraz inne zmartwienie O jakość hmb z lonzy się nie boję, ale dzialania hmb raczej nie czuję.
Pzdr.

W przypadku hmb, jak i większości suplementów istnieje tzw. wrażliwość osobnicza... To znaczy, że na dany suplement ktoś może reagować bardzo dobrze, a inny słabo. Dla tego w metodyce badawczej wymagane są grupy reprezentatywne, tj. pow. 20-tu osób. Może Ty jesteś akurat w tej grupie, która na hmb reaguje słabo?...

Sławku odpowiesz na moje powyzsze pytanie ?