Ciekawy art-T3 a poziom testosteronu,do przetłumaczenia

Found this tonight:

Thyroid hormones: their role in testicular steroid...[Arch Androl. 2003 Sep-Oct] - PubMed Result

Some very important and intresting quotes:

"T3 directly increases Leydig cell LH receptor numbers and mRNA levels of steroidogenic enzymes and steroidogenic acute regulatory protein. It stimulates basal and LH-induced secretion of progesterone, testosterone, and estradiol by Leydig cells. Steroidogenic factor-1 acts as a mediator for T3-induced Leydig cell steroidogenesis. Although the role of T3 on sperm, germ, and peritubular cells has not yet been completely studied, it is clear that T3 directly regulates Sertoli and Leydig cell functions."

Testicular dysfunction in men with primary hypothy...[Clin Endocrinol (Oxf). 2000] - PubMed Result

"OBJECTIVE: Primary hypothyroidism can cause disturbances in normal gonadal function. The aim of this study was to investigate the relationship in men between hypogonadism and primary hypothyroidism and the extent to which free and total testosterone levels rose after introduction of replacement thyroxine. DESIGN: Paired study of patients in a hypothyroid and thyroxine treated state. PATIENTS: Ten men with primary hypothyroidism. MEASUREMENTS: Free and total testosterone, gonadotrophin and prolactin levels before and after thyroxine replacement therapy. RESULTS: Low free testosterone levels (161 +/- 62 pmol/l) demonstrated at the time the men were hypothyroid rose significantly with the commencement of thyroxine replacement (315 +/- 141 pmol/l; P < 0.001). Gonadotrophin levels were not elevated consistent with hypogonadotrophic hypogonadism. Hyperprolactinaemia, which can occur in primary hypothyroidism and cause hypogonadotrophic hypogonadism, was not present in the majority of these patients. However a reduction in prolactin level was evident with thyroxine replacement and a rise in free testosterone levels. CONCLUSION: This suggests an effect of hypothyroidism on gonadotrophin secretion at the level of the hypothalamus-pituitary, either directly or through modulation of prolactin secretion. Low free testosterone may also be a contributing factor to some of the symptoms and signs of hypothyroidism in men."

Konkluzja: Niedoczynność tarczycy ma wpływ na powstawanie gonadotropin na osi podwzgórze - przysadka albo pośrednio poprzez wpływ na sekrecję prolaktyny (z wcześniejszych zdań wynika że leczenie niedoczynności obniżyło prolaktynę co z kolei spowodowało podniesienie poziomu testosteronu). Niski poziom wolnego testosteronu może być oznaką niedoczynności tarczycy.
Taki wniosek z tego całego nie chciało mi się tłumaczyć z resztą kiepski ze mnie tłumacz.
Kurcze ja mam niski poziom wolnego testa ale wskaźniki hormonów tarczycy były w miarę w porządku. Ciekawe czy po moim ostatnim cyklonie na t4 i t3 mogłoi się coś zmienić w kwestii wolnego testa.
Łap soga stary za tego arta. Mnie się przydał