CLA

Witam, kolega chce zacząć brać CLA. Ja osobiście nie mam z tym środkiem doświadczenia. Zatem mam do Was pytanie jakiej firmy polecacie, oraz jak dawkować.

W jakim celu chce to brać?

Jako wspomagacz spalania tkanki tłuszczowej.

olimp jest chyba w dobrej cenie, ale cudów po tym bym się nie spodziewał.

IMO min 4g na dobę

A ja bym w ogóle nie polecał tego brać poczytajcie sobie opisy badania nad cla na naukowych forach działanie tego kwasu jeśli chodzi o spalanie tkanki tłuszczowej faktycznie wyszło pozytywnie ale tylko w przypadku szczurów po podawaniu cla ludziom okazało się że efektów nie ma praktycznie żadnych na domiar złego jedna z subst. zawarta w cla podawana zbyt długo okazała się szkodliwa. proponuje zagłębic się w wikipedi i innych żrodłach.

bezpieczenstwo:

Safety profile of conjugated linoleic acid in a 12-month trial in obese humans.
Whigham LD, O'Shea M, Mohede IC, Walaski HP, Atkinson RL.

Department of Medicine and Nutritional Sciences, University of Wisconsin, Madison 53706, USA.
Abstract
Conjugated linoleic acid (CLA) is marketed in numerous commercially available dietary supplements, but few studies have looked at the long-term safety of this product. The current study evaluated the safety of one CLA product (Clarinol) over a one-year period in obese humans who were generally healthy. This was a randomized, double-blind study consisting of three phases in which subjects were given 6 g/day of CLA or placebo. Phase 1 was a low calorie diet (13 kcal/kg desirable weight) for 12 weeks or until 10-20% of initial body weight was lost. In phase 2, from weeks 12 to 28, subjects were re-fed a diet providing 25-30 kcal/kg of desirable body weight. Phase 3 was open label, with subjects from both groups taking CLA from weeks 28 to 52. At biweekly visits, subjects completed a questionnaire evaluating side effects and adverse events. Blood was taken for assay of liver function, glucose, insulin, serum lipids, blood counts, and general chemistry. Overall, body composition did not differ between groups. Laboratory tests showed no adverse effects of CLA. Adverse events and side effects were less in the CLA group compared to placebo. We conclude that CLA as Clarinol is safe for use in obese humans for at least one year.

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Racje jednak - zdecydowana wiekszośc badań dotyczacych i skutecznosci i bezpieczeństwa - przy długotrwałym stosowaniu - dotyczy modelu zwierzęcego. Przy badaniach na ludziach pojawiały się nieraz sprzeczne doniesienia (wg niektórych CLA pogarszało wrazliwosc na insulinę, wg innych poprawiało, wg jeszcze innych nie miało wpływu).

Tutaj ciekawa publikacja:

Conjugated linoleic acid supplementation, insulin sensitivity, and lipoprotein metabolism in patients with type 2 diabetes mellitus1,2,3
Fiona Moloney, Toh-Peng Yeow, Anne Mullen, John J Nolan and Helen M Roche
1 From the Nutrigenomics Research Group, Department of Clinical Medicine, Trinity Centre for Health Sciences, Dublin (FM, AM, and HMR), and the Metabolic Research Unit, St James’s Hospital, Dublin (T-PY and JJN).
Background: Some animal studies have suggested that conjugated linoleic acid (CLA) supplementation may have therapeutic potential with respect to insulin sensitivity and lipid metabolism, which are important cardiovascular disease (CVD) risk factors associated with type 2 diabetes mellitus.

Objective: We investigated the effect of CLA supplementation on markers of glucose and insulin metabolism, lipoprotein metabolism, and inflammatory markers of CVD in subjects with type 2 diabetes.

Design: The study was a randomized, double-blind, placebo-controlled trial. Thirty-two subjects with stable, diet-controlled type 2 diabetes received CLA (3.0 g/d; 50:50 blend of cis-9,trans-11 CLA and trans-10,cis-12 CLA) or control for 8 wk. A 3-h 75-g oral-glucose-tolerance test was performed, and fasting plasma lipid concentrations and inflammatory markers were measured before and after the intervention.

Results: CLA supplementation significantly increased fasting glucose concentrations (6.3%; P < 0.05) and reduced insulin sensitivity as measured by homeostasis model assessment, oral glucose insulin sensitivity, and the insulin sensitivity index (composite) (P = 0.05). Total HDL-cholesterol concentrations increased by 8% (P < 0.05), which was due to a significant increase in HDL2-cholesterol concentrations (P < 0.05). The ratio of LDL to HDL cholesterol was significantly reduced (P < 0.01). CLA supplementation reduced fibrinogen concentrations (P < 0.01) but had no effect on the inflammatory markers of CVD (C-reactive protein and interleukin 6).

Conclusions: CLA supplementation had an adverse effect on insulin and glucose metabolism. Whereas CLA had positive effects on HDL metabolism and fibrinogen, a therapeutic nutrient should not be associated with potentially adverse effects on other clinical markers of type 2 diabetes.

- należy pamietac jednak iż w/w padanie wykonane nyło na cukrzykach.


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Moim zdaniem CLA moze byc raczej bardziej przydatne przy tzw "wychodzeniu z diety", niż faktycznej redukcji tkanki tłuszczwej. Są publikacje, w tym - na ludziach - które wykazują iż zwiększona podaz CLA - w okresie tzw odzywskiwania wagi korzystnie wpływa na skład ciała.